一种吴茱萸总生物碱新的医药用途

New medical application of fructus evodiae total alkaloid

Abstract

The invention relates to new medical application of a fructus evodiae total alkaloid, namely, the application of the fructus evodiae total alkaloid in the preparation of a medicament for preventing and treating hepatic fibrosis. The fructus evodiae total alkaloid is a general name of indole-quinoline and quinolone alkaloids extracted and separated from fructus evodiae, and the content of the total alkaloid is between 20 and 60 percent. The fructus evodiae total alkaloid shows a certain treating effect in a therapeutic action experiment on rat hepatic fibrosis induced by carbon tetrachloride and has an excellent clinical application prospect. The fructus evodiae total alkaloid has an exact anti-hepatic fibrosis function and can be combined with auxiliary materials for preparing an anti-hepatic fibrosis medicament.
一种吴茱萸总生物碱新的医药用途,即吴茱萸总生物碱在制备预防和治疗肝纤维化药物中的应用。吴茱萸总生物碱是自吴茱萸中提取、分离得到的吲哚喹啉类和喹诺酮类生物碱的总称,总生物碱含量20~60%。本发明在大鼠四氯化碳诱导肝纤维化的治疗作用实验中显示出一定的治疗作用,有较好的临床应用前景。说明吴茱萸总生物碱具有确切的抗肝纤维化作用,可与辅料结合制备抗肝纤维化药物。

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Patent Citations (1)

    Publication numberPublication dateAssigneeTitle
    CN-1096681-ADecember 28, 1994张俊才Medicinal powder for treating hepatic disease

NO-Patent Citations (1)

    Title
    田光辉等.吴茱萸果实中脂溶性成分的研究.《中药材》.2008,第31卷(第03期),382-385.

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